25 Doses per bottle 4mg CBD and 4mg THC in .5ML Start with a dose of .5ml under the tongue, and wait at least 1 hour to see if that dose gives you relief from your symptoms. If you need to increase the dose, do so in small amounts, and only as necessary. Times and reactions vary for each individual. Matter concentrated tinctures are taken by dropper under the tongue. Holding the dispensed tincture oil under the tongue for a minute or so, will allow the cannabinoids to pass through the mucous membrane and tiny blood vessels in your mouth in order to go directly into your bloodstream. This results in quicker onset and peak times than felt with an edible because there is no digestion needed.